Table 2.
Occurrence of ICPI-induced organ inflammation on interim 18FDG PET
| Immunotherapy-induced inflammation on PETInterim1 and/or PETInterim2 | Exploratory cohort, Nice | Validation cohort, Genova |
|---|---|---|
| All organs | ||
| Yes | 67 (72.8) | 39 (86.7) |
| No | 25 (27.2) | 6 (13.3) |
| Pneumonitis | ||
| Yes | 16 (17.4) | 9 (20.0) |
| No | 76 (82.6) | 36 (80.0) |
| Thyroiditis | ||
| Yes | 17 (18.5) | 4 (8.9) |
| No | 75 (81.5) | 42 (91.1) |
| Gastritis | ||
| Yes | 20 (21.7) | 9 (20.0) |
| No | 72 (78.3) | 36 (80.0) |
| Midgut/hindgut inflammation | ||
| Yes | 31 (33.7) | 18 (40.0) |
| No | 61 (66.3) | 27 (60.0) |
| Other organs’ inflammation | ||
| Yes | 9 (9.8) | 2 (4.4) |
| No | 83 (90.2) | 43 (95.6) |
Other organ: pancreatitis, ENT inflammation, osteo-articular inflammation, esophagitis, mesenteric panniculitis, mediastinal granulomatosis occurrence, pleuritis