. 2022 May 10;49(11):3852–3869. doi: 10.1007/s00259-022-05817-6

Table 4.

Commonly used TBR thresholds for amino acid PET in paediatric gliomas

Clinical Indication	Amino acid Radiopharmaceutical	Method	Threshold	Reference
Differentiation between neoplastic a non-neoplastic brain lesion	[¹⁸F]FET	TBRmax	1.6	[71]
	[¹¹C]MET	TBR max	1–1.5	[56, 58, 102]
	[¹⁸F]DOPA	TBRmax	1	[81, 82]
Tumour Grading	[¹⁸F]FET	TAC curve shape	N.A	[72]
	[¹¹C]MET	N.R	N.R
	[¹⁸F]DOPA	TSRmax	1	[81, 82]
Prognostic value	[¹⁸F]FET	TBR max and TAC curve shape	1.6	[71, 72]
	[¹¹C]MET	SUVmax	3	[65]
	[¹⁸F]DOPA	TSRmax	1	[81, 82]
Tumour Relapse	[¹⁸F]FET	TBRmax	1.6	[71]
	[¹¹C]MET	SUVmax	3	[65]
	[¹⁸F]DOPA	Not available	Not available	Not available

N.R. = not reported, N.A. = not applicable