Table 3.

Mediation Results for the Association Between Hostile Resistance in Session 10 and Poor Subsequent Symptom Change.

Mediation Model	n	β	SE	t (df)	p	r	CI 95%
Adherence x Time  Hostile Resistance x Time	52	0.18 −1.91	0.27 0.89	0.71 (85) −2.13 (85)	.48 .04	.01 −.29	−.18, .36 −.52, −.02
Adherence-Squared x Time  Hostile Resistance x Time	52	−0.14 −2.11	0.16 0.93	−0.86 (84) −2.27 (84)	.39 .03	−.12 −.31	−.38, .16 −.53, −.04
Off-Protocol x Time  Hostile Resistance x Time	53	−0.74 −1.83	1.02 0.87	−0.72 (87) −2.11 (87)	.47 .04	−.10 −.28	−.36, .17 −.51, −.01
Off-Protocol-Squared x Time  Hostile Resistance x Time	53	0.16 −1.84	3.12 0.89	0.05 (86) −2.08 (86)	.96 .04	.01 −.28	−.26, .28 −.51, −.01
Working Alliance-Client x Time  Hostile Resistance x Time	31	0.22 −1.60	0.32 1.12	0.68 (51) −1.43 (51)	.50 .16	.13 −.26	−.24, .46 −.11, .56
Working Alliance-Therapist x Time  Hostile Resistance x Time	46	0.24 −1.80	0.27 0.90	0.90 (77) −2.01 (77)	.37 .048	.13 −.29	−.16, .41 < .001, .54

Note: Results were generated using hierarchical linear modeling. Mediation is suggested when the Mediator x Time term is significant and the Hostile Resistance x Time term is non-significant. Hostile resistance and all putative mediators were measured at Session 10 with the exception of the two working alliance variables, which are residualized change scores. In these analyses, a negative Hostile Resistance x Time effect indicates that hostile resistance predicts a slower rate of change on the Panic Disorder Severity Scale (PDSS); a negative Mediator x Time effect indicates that a higher level of that mediator predicts a faster rate of PDSS change.