TABLE 1.

Demographic information

	Estradiol		Placebo
Measure	Mean (SD)	Range	Mean (SD)	Range
Age	55.35 (2.68)	50–59	56.55 (2.67)	52–60
CCI (% complaints endorsed)	18.71 (12.2)	1.8–47	21.36 (13.5)	0–51
BDI	3.1 (3.1)	0–10	2.95 (3.2)	0–12
BMI	24.49 (3.1)	20–29	24.5 (2.8)	20.3–30.1
Years since menopause	6.55 (4.3)	2–16	7.2 (3.9)	2–15
STRAW+10 score (1/2)	13/7		10/10
MSC at screening	14.0 (8.2)	2–30	16.2 (8.0)	6–37
MSC post-treatment a	17.27 (10.4)	2–36	22.2 (12.3)	6–50
MMSE	29.05 (1.05)	26–30	28.9 (1.41)	26–30
Education (years)	16.1 (1.9)	13–20	15.8 (2.1)	12–20
Prior HT use (yes/no)	2/18		7/13

Note: All numbers are displayed as mean (standard deviation) unless stated.

Abbreviations: BDI, Beck Depression Inventory; BMI, Body Mass Index; CCI, Cognitive Complaint Index; HT, Hormone Replacement Therapy; MMSE, Mini-Mental State Exam; MSC, Menopause Symptom Checklist; STRAW+10, Stages of Reproductive Aging, 10-year revision.

^*p < 0.05.

^an = 32, not 40.