Table 1.

Italian health technology assessment mechanism for medical devices: national and regional level.

Level	HTA mechanism	Key features
National Level	National HTA Program for MDs regulated by national ordinances	Structured pathway for the HTA of MDs run by a central governmental hub which networks with various spokes, including the Regions and other research and healthcare centers Standardized and evidence-based methodological procedures that cover all phases of the HTA (i.e., proposal and prioritization, assessment, appraisal, and dissemination)
Regional level	Regional HTA initiatives for MDs regulated by regional ordinances	Regional HTA pathways and methodologies appear to be heterogeneous About half the Regions seem to have formally acknowledged the NHTAPMD (11 Regions out of 21)

HTA, Health Technology Assessment; MDs, medical devices; NHTAPMD, National HTA Program for Medical Devices.