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. 2022 Aug 10;9:946766. doi: 10.3389/fcvm.2022.946766

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Copyright © 2022 He, Wang, Sun, Li and Feng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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NG reduced HG-induced oxidative stress and apoptosis in H9C2 cells. (A) Representative images of DCFH-DA staining for each group, fluorescence microscope (200×). Data are expressed as mean ± SD (n = 3), *P < 0.05 vs. Ctrl group; ^#P < 0.05 vs. DM group. (B) Evaluation of apoptosis by flow cytometry using Annexin V staining. Data are expressed as mean ± SD (n = 3), *P < 0.05 vs. Ctrl group; ^#P < 0.05 vs. DM group. (C) Quantitative analysis of the protein expression of IL-6, HO-1, and NQO1 in H9C2 cells. Data are expressed as mean ± SD (n = 3), *P < 0.05 vs. Ctrl group; ^#P < 0.05 vs. DM group.