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. 2022 Aug 10;13:888533. doi: 10.3389/fphar.2022.888533

FIGURE 2.

FIGURE 2

Sample clustering and soft-thresholding power determination. (A) Heatmap of the genes involved in WGCNA. (B) Clustering dendrogram of the gene expression of the synovial tissue from 26 OA patients and 12 healthy donors after excluding the outliers. Clustering was based on Euclidean distance calculated with variance stabilized expression level. (C) Analysis of scale independence and mean connectivity of the gene network at various soft-thresholding powers to determine the scale-free fit index.