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. 2022 Aug 10;13:968288. doi: 10.3389/fneur.2022.968288

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Copyright © 2022 Nordström, Forsse, Jakobsen, Mölström, Nielsen, Toft and Ungerstedt.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Acute effects of cardiopulmonary bypass (CPB) and two levels of mean arterial blood pressure (MAP) on lactate/pyruvate (LP) ratio obtained from a microdialysis catheter placed in the jugular bulb (upper panel) and the simultaneous MAP levels (lower panel). Data are shown as median (IQR). The interrupted line (upper panel) indicates reference level (Mean) for LP ratio in human jugular venous blood (43). *Significant difference from baseline. **Significant difference between corresponding datapoints by one-way analysis of variance and corrected for multiple comparisons using the Bonferroni test (α = 0.006). Values are median and error with inter quartile range (n = 10). Figures by permission from (43).