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Biological functional validation of MSH2 in GBM cell. (A) Silencing efficiency of MSH2. CCK8 assay (B), EDU assay (C), and colony formation assay (D) showing the effect of MSH2 knockdown on proliferation of U-118 MG cells. (E) Transwell assay indicating that MSH2 depletion markedly weakens migration and invasion by U-118 MG cells (*p < 0.05, **p < 0.01, and ***p < 0.001, n = 3).
