Table 1.
Relationship between periventricular white matter hyperintensities (PWMHs) and deep white matter hyperintensities (DWMHs) volume and demographic, clinical, and imaging data.
| PWMH volume | DWMH volume | |||||||
|---|---|---|---|---|---|---|---|---|
| Yes | No | P | r (P) | Yes | No | P | r (P) | |
| Female | 6.2 ± 7.3 | 6.6 ± 8.0 | 0.765 | - | 5.2 ± 5.8 | 5.6 ± 6.4 | 0.660 | - |
| Age (year) | - | - | - | 0.495 (<0.001) | - | - | - | 0.500 (<0.001) |
| Hypertension | 7.8 ± 8.7 | 3.5 ± 3.2 | 0.001 | - | 6.1 ± 6.7 | 3.8 ± 4.0 | 0.025 | - |
| Diabetes mellitus | 6.4 ± 9.6 | 6.4 ± 7.0 | 0.964 | - | 4.8 ± 6.7 | 5.5 ± 5.9 | 0.535 | - |
| Hyperlipidemia | 7.9 ± 8.6 | 5.6 ± 7.1 | 0.088 | - | 5.7 ± 6.1 | 5.3 ± 6.1 | 0.702 | - |
| Smoking | 6.7 ± 9.7 | 6.3 ± 6.9 | 0.749 | - | 4.9 ± 6.6 | 5.6 ± 5.9 | 0.547 | - |
| DMVs score | - | - | - | 0.286 (<0.001) | - | - | - | 0.161 (0.047) |
| CBF of white matter, mL/100 g-tissue/min | - | - | - | −0.163 (0.045) | - | - | - | −0.231 (0.004) |
| CBF of gray matter, mL/100 g-tissue/min | - | - | - | −0.073 (0.375) | - | - | - | −0.101 (0.218) |
| ALPS index | - | - | - | −0.264 (0.001) | - | - | - | −0.260 (0.001) |
DMVs, deep medullary veins; ALPS index, index for diffusion tensor image analysis along the perivascular space.