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Time to EDA-3 for all IgM-metrics used to assess ITMS. Association of ITMS and time to EDA-3. Kaplan-Meier survival curves and results of the logrank test for (A) IgM-index>0.1; (B) IgMIF>0% according to Reiber; and (C) OCMB; and the probability of EDA-3 within 24 months from diagnostic LP; EDA, Evidence of Disease Activity; Ig, immunoglobulin; IF, intrathecal fraction; OCMB, oligoclonal IgM bands.
