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. Author manuscript; available in PMC: 2022 Aug 24.
Published in final edited form as: Urol Oncol. 2020 Sep 15;39(5):295.e1–295.e8. doi: 10.1016/j.urolonc.2020.08.027

Table 1.

Clinical survey responses regarding quantification of pattern 4 in a variety of needle biopsy and radical prostatectomy scenarios

Question All Responses (N=834)* Urology (N=580) Radiation Oncology (N=186)
Q5: Do you EVER utilize the quantity of pattern 4 on NB in clinical decision making? YES: 80% (N=661)
NO: 20% (N=168)
[Responses: 829]		 YES: 82% (N=470)
NO: 18% (N=106)
[Responses: 576]		 YES: 76% (N=141)
NO: 24% (N=45)
[Responses: 186]
Q7: In NB with highest Grade group 3 prostate cancer, would it be valuable to know the quantity of pattern 4 (e.g. 60% vs. 90% pattern 4)? YES: 62% (N=284)
NO: 38% (N=176)
[Responses: 460]		 YES: 60% (N=202)
NO: 40% (N=134)
[Responses: 336]		 YES: 70% (N=64)
NO: 30% (N=28)
[Responses: 92]
Q8: One NB has Grade group 3 involving 10% of a core; 3 other cores show Grade group 2. Is it valuable to know if the 3 cores had 10% vs. 40% pattern 4? YES: 51% (N=237)
NO: 49% (N=223)
[Responses: 460]		 YES: 54% (N=180)
NO: 46% (N=156)
[Responses: 336]		 YES: 51% (N=47)
NO: 49% (N=45)
[Responses: 92]
Q9: One NB has Grade group 4 involving 10% of a core; 3 other cores show Grade group 3. Is it valuable to know if the 3 cores had 60% vs. 90% pattern 4? YES: 30% (N=137)
NO: 70% (N=323)
[Responses: 460]		 YES: 30% (N=100)
NO: 70% (N=236)
[Responses: 336]		 YES: 35% (N=32)
NO: 65% (N=60)
[Responses: 92]
Q11: Would it be valuable to know the % pattern 4 for GS 7 (Grade groups 2–3) on RP? YES: 53% (N=316)
NO: 47% (N=280)
[Responses: 596]		 YES: 56% (N=235)
NO: 44% (N=188)
[Responses: 423]		 YES: 50% (N=64)
NO: 50% (N=64)
[Responses: 128]
Q12: In RP specimens with GS 7 (Grade groups 2–3) and a reported “tertiary” Gleason pattern 5, do you assume that the “tertiary” pattern is minor (<5%) or could be any amount (as long as 3rd most common)? MINOR: 52% (N=307)
ANY: 48% (N=289)
[Responses: 596]		 MINOR: 53% (N=224)
ANY: 47% (N=199)
[Responses: 423]		 MINOR: 48% (N=62)
ANY: 52% (N=66)
[Responses: 128]
Q13: In RP specimens with GS 7 (Grade groups 2–3), does a minor (<5%) component of Gleason pattern 5 affect further therapy? YES: 43% (N=259)
NO: 57% (N=337)
[Responses: 596]		 YES: 43% (N=183)
NO: 57% (N=239)
[Responses: 422]		 YES: 45% (N=58)
NO: 55% (N=70)
[Responses: 128]
*

Also includes responses from Medical Oncologists (N=46) and ‘Other’ (N=22)

NB: needle biopsy; GS: Gleason score; RP: radical prostatectomy