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. Author manuscript; available in PMC: 2022 Aug 24.
Published in final edited form as: Methods Mol Biol. 2015;1335:205–221. doi: 10.1007/978-1-4939-2914-6_14

Fig. 7.

Fig. 7.

CNO treatment of Hep-Dq mice leads to pronounced increases in blood glucose levels. Using AAV technology (see text for details), we generated mice that expressed either Dq or EGFP selectively in hepatocytes (Hep-Dq and Hep-EGFP control mice, respectively). Male mice (genetic background: C57BL/6; age: ~12 weeks) that had been fasted overnight for 12 hr received a single injection of CNO (10 mg/kg i.p.), and blood glucose levels were measured at the indicated time points (M. Rossi, et al., unpublished results). Data are given as means ± SEM (n=8 per group).