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. 2022 Jul 8;24(3):563. doi: 10.3892/etm.2022.11500

Figure 4.

Figure 4

Associations of LTBP2 expression with clinicopathological features and pan-cancer analysis. (A and B) Boxplots revealed that LTBP2 was under-expressed in tumor tissues compared with normal control tissues in (A) TCGA-PRAD dataset and (B) TCGA combined with GTEx dataset. (C-E) Boxplot indicating LTBP2 expression in different (C) Gleason-score, (D) AJCC T stage, (E) PSA-value of PCa samples from TCGA-PRAD dataset. (F) The ROC curves revealed the efficiency of LTBP2 expression levels to distinguish PCa tissues from normal prostate tissues. (G and H) Boxplots displaying the LTBP2 expression using pan-cancer analysis. (I and J) Boxplot indicating LTBP2 expression in various clinicopathological features using pan-cancer analysis. Subgroup comparison between different tumors in G-I were demonstrated using *P<0.05, **P<0.01 and ***P<0.001. LTBP2, latent transforming growth factor β-binding protein 2; TCGA, The Cancer Genome ATLAS; PRAD, prostate adenocarcinoma; GTEx, Genotype-Tissue Expression; AJCC, American Joint Committee on Cancer; PSA, prostate-specific antigen; PCa, prostate cancer; ROC, receiver operating characteristic.