Table 2.
Jadad Score of randomized clinical trials included in the meta-analysis
| Trial | Study ID | Randomization | Randomization appropriate | Double-blind | Blinding appropriate | Description of withdrawals and dropouts | Total score |
|---|---|---|---|---|---|---|---|
| NR | NCT01285609 | 1 | 1 | 1 | 1 | 1 | 5 |
| Govindan et al. J Clin Oncol 2017 | |||||||
| IMpower130 | NCT02367781 | 1 | 1 | 0 | 0 | 1 | 3 |
| West et al. Lancet Oncol 2019 | |||||||
| IMpower131 | NCT02367794 | 1 | 1 | 0 | 0 | 1 | 3 |
| Jotte et al. J Thorac Oncol 2020 | |||||||
| IMpower132 | NCT02657434 | 1 | 1 | 0 | 0 | 1 | 3 |
| Nishio et al. J Thorac Oncol 2021 | |||||||
| IMpower150 | NCT02366143 | 1 | 1 | 0 | 0 | 1 | 3 |
| Socinski et al. J Thorac Oncol 2021 | |||||||
| KEYNOTE-189 | NCT02578680 | 1 | 1 | 1 | 1 | 1 | 5 |
| Rodríguez-Abreu et al. Ann Oncol 2021 | |||||||
| KEYNOTE-407 | NCT02775435 | 1 | 1 | 1 | 1 | 1 | 5 |
| Paz-Ares et al. N Engl J Med 2018 | |||||||
| TASUKI-52 | NCT03117049 | 1 | 1 | 1 | 1 | 1 | 5 |
| Sugawara et al. Ann Oncol 2021 | |||||||
| CheckMate 9LA | NCT03215706 | 1 | 1 | 0 | 0 | 1 | 3 |
| Paz-Ares et al. Lancet Oncol 2021 | |||||||
NR not reported