Table 1.
The physicochemical parameters, antigenicity and allergenicity of NOM and FNOM Proteins.
| Characteristics | FNOM | NOM |
|---|---|---|
| Number of amino acids | 559 | 337 |
| Molecular weight (dalton) | 60778.29 | 37513.55 |
| Total number of negatively charged residues (Asp + Glu) | 43 | 19 |
| Total number of positively charged residues (Arg + Lys) | 59 | 32 |
| Theoretical isoelectric point (pI) 5.14 | 9.53 | 9.62 |
| Estimated half-life | 4.4 h (mammalian reticulocytes, in vitro). >20 h (yeast, in vivo). >10 h (Escherichia coli, in vivo). | >20 h (mammalian reticulocytes, in vitro). >20 h (yeast, in vivo). ? (Escherichia coli, in vivo). |
| Instability index | 33.27 | 35.75 |
| Aliphatic index | 93.60 | 97.92 |
| Grand average hydropathy | −0.101 | 0.177 |
| Antigenicity | 0.5507 | 0.5999 |
| Allergenicity | Non-allergen | Non-allergen |