Figure 5.

CD14 expression on monocytes mediates the interleukin (IL)-6 response to respiratory syncytial virus fusion (RSV-F). (a) The IL-6 protein response after 4, 18, and 24 hours of stimulation by RSV-pre-F and post-F (10 µg/mL), by peripheral blood mononuclear cells of 2 healthy controls (HC) and the index patient (IP). One experiment, performed in duplicates, lines indicate mean per individual (+standard deviation). (b) The IL-6 protein response during 24 hours of stimulation by RSV-pre-F (5 µg/mL) by Percoll-isolated monocytes of 2 healthy controls, the index patient, and his father. One experiment, lines indicate mean per individual.