Table 3.

Inclusion and exclusion criteria

Inclusion criteria	Exclusion criteria
Histologically basal cell carcinoma or cytologically located confirmed, in the head previously and neck untreated region cutaneous	Other malignancy at the time of inclusion
Solitary tumors, with largest diameter up to 3 cm, in the region where curative (R0) surgery is feasible	Lesions not suitable for treatment with GET (invasion into the bone, infiltration of large vessels)
Age 18-years or older	A life-threatening infection and/or severe heart failure and/or liver failure and/or other life-threatening systemic diseases
Life expectancy > 3 months	Significantly reduced lung function, which requires the determination of DLCO. Patients should not be treated if DLCO is abnormal
Physical performance in accordance with the Karnofsky scale ≥ 70 or < 2 in accordance with World Health Organization (WHO) scale	Treatment with immunosuppressive drugs, steroids and other drugs that would affect poor wound healing
The patient must be capable of understanding the treatment procedure and possible adverse events, which may arise during treatment	Age under 18-years
The patient must be capable of signing the informed consent to participate in the clinical study (voluntary and conscientious consent after education)	Major disruptions in the coagulation system (who does not respond to the standard therapy – replacement of vitamin K or freshly frozen plasma)
Prior multidisciplinary to inclusion in advisory the trial, team the patient meeting must be presented at a	A chronic decline in the kidney function (creatinine > 150 μmol/L)
	Epilepsy
	Pregnancy and breast-feeding
	The patient’s incapability of comprehending the purpose or course of the trial, or not agreeing to be included in the trial
	Patients unwilling or unable to comply with the protocol requirements and scheduled visits

DLCO = Diffusing Capacity of the Lungs for carbon monoxide; GET = gene electrotransfer