Table 3.

Univariate analyses of overall survival

Factor	p-value	HR (95% CI)
Age
< 65		1
≥ 65	0.002	1.59 (1.18 – 2.15)
Gender
Male		1
Female	0.001	0.59 (0.43 – 0.81)
Smoking status
never		1
current or former	0.115	1.50 (0.91 – 2.47)
Histology
adenocarcinoma or NOS		1
squamous cell carcinoma	0.111	1.28 (0.95 – 1.73)
EGFR statusa (positive vs negative)
negative		1
positive	0.111	0.56 (0.27 – 1.14)
Clinical TNM stage	0.027*
I		1
II	0.034	1.44 (1.03 – 2.02)
IIIA	0.025	1.57 (1.06 – 2.34)
Clinical T stage	0.001*
T1		1
T2	0.882	0.97 (0.69 – 1.38)
T3 or T4	0.001	1.86 (1.29 – 2.68)
Clinical N stage	0.317*
N0		1
N1	0.958	0.99 (0.67 – 1.46)
N2	0.137	1.44 (0.89 – 2.34)
Pathological TNM stage	0.003*
I		1
II	0.030	1.46 (1.04 – 2.06)
IIIA	0.001	1.90 (1.29 – 2.79)
Pathological T stage	0.007*
T1		1
T2	0.019	1.49 (1.07 – 2.07)
T3 or T4	0.004	1.92 (1.23 – 2.98)
Pathological N stage	0.002*
N0		1
N1	0.054	1.48 (0.99 – 2.20)
N2	0.001	1.93 (1.29 – 2.87)

^aonly in non-squamous NSCLC; ^*for the whole variable