Figure 3.
Quantitative comparison of changes in nrCBV, FLAIR volume, and ADC after IDH inhibitor treatment. After 3–6 weeks of IDH inhibitor treatment, there was (A, B) a significant increase in nrCBV (P = .004) (C) and no change in FLAIR volume (P = .23) (D) or ADC (P = .52). After 2–4 months of IDH inhibitor treatment, (E, F) nrCBV, (G) FLAIR volume, and (H) ADC appeared to stabilize. Asterisks (*) indicate P < .05. IDH, isocitrate dehydrogenase; nrCBV, normalized relative cerebral blood volume; ADC, apparent diffusion coefficient.