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. 2022 Aug 24;12:14442. doi: 10.1038/s41598-022-18272-y

Table 6.

Adverse events during the clinical trial.

Group Placebo NMN NMN NMN NMN
Subject No. 9 11 16 19 23
Adverse Event Loose stool Common cold High blood pressure Loose stool Acne vulgaris
Occurrence of adverse events Oral administration period Oral administration period Oral administration period Oral administration period Oral administration period
Extent of symptom Mild Moderate Mild Mild Mild
Availability of treatment Without With Without Without Without
Outcome Recovery Recovery Remission Recovery Recovery
Causality Unrelated Unrelated Unrelated Unrelated Unrelated
Reasons for determining causality The causal relationship with this test food was irrelevant due to an incidental event The causal relationship with this test food was irrelevant because of the infection The causal relationship with this test food was irrelevant due to an incidental event The causal relationship with this test food was irrelevant due to an incidental event The causal relationship with this test food was irrelevant due to an incidental event
Resumption or discontinuation of the study Resumption Resumption Resumption Resumption Resumption