Table 2.
Analysis to Find Baseline Characteristics That Are Predictive of a Patient Self-Reporting BII—Metals
| Baseline characteristic | BII vs non-BII (Cohort A vs Cohort B) |
BII vs mastopexy (Cohort A vs Cohort C) |
|||
|---|---|---|---|---|---|
| Reference category |
Odds ratio | P value | Odds ratio | P value | |
| Tobacco history | Never | ||||
| Former | 1.304 | 0.5634 | 2.529 | 0.0725 | |
| Current | >999 | 0.0864 | >999 | 0.0734 | |
| Marijuana use | Never | ||||
| Former | 1.277 | 0.6479 | 3.486 | 0.0758 | |
| Current | >999 | 0.0156 | 1.163 | 0.8390 | |
| Medications | |||||
| Antibiotics (yes/no) | No | 2.538 | 0.1096 | 13.820 | 0.0138 |
| Aspirin/NSAID (yes/no) | No | 14.461 | <0.0001 | 10.615 | <0.0001 |
| Prescription pain medications (yes/no) | No | >999 | 0.0032 | 1.568 | 0.5076 |
| Other herbal/nonprescription medicines (yes/no) | No | 4.636 | 0.0060 | 1.325 | 0.5171 |
| Any allergy (yes/no) | No | 1.405 | 0.4769 | 4.909 | 0.0005 |
| Allergy: gluten (yes/no) | No | 7.977 | 0.0566 | >999 | 0.0015 |
| Allergy: wheat (yes/no) | No | 4.261 | 0.2023 | >999 | 0.0177 |
| Tattoos (yes/no) | No | 2.681 | 0.0172 | 1.043 | 0.2309 |
BII indicates those patients seeking explantation because they believe their implants are responsible for their symptoms. Cohort A: patients with self-reported BII requesting explantation; Cohort B: patients requesting implant exchange or explantation without self-reported BII; Cohort C: patients with mastopexy (without soft-tissue support or implants). The odds ratios and P values are from a logistic regression analysis with group as the dependent variable and the baseline characteristic as the explanatory variable. The P value is for a 2-sided test of the null hypothesis that the true odds ratio equals 1. BII, breast implant illness; NSAID, nonsteroidal anti-inflammatory drug.