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. 2022 Aug 20;15:1715–1727. doi: 10.2147/CCID.S372229

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© 2022 Wang et al.

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The effect of luteolin on proliferation, angiogenesis and migration in HMEC-1. (A) HMEC-1 cells were treated with different concentration of luteolin (0, 1, 5, 10 μM) and SSD for 24, 48 and 72 h, the cell viability was analyzed by CCK-8 assay. (B) HMEC-1 were treated with different concentration of luteolin (0, 1, 5, 10 μM) and SSD for 8 h, tubule formation experiment was used to observe the lumen structure of HMEC-1 cells. (C) HMEC-1 cells were treated with different concentration of luteolin (0, 1, 5, 10 μM) and SSD for 48 h, migration was analyzed by scratch assays. Scale bar =200 μm. The values were presented as mean ± SD (n=3). *P<0.05; **P<0.01 and ***P<0.001 versus the control group.