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. 2021 Dec 31;2(6):511–521. doi: 10.37349/etat.2021.00061

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© The Author(s) 2021.

This is an Open Access article licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Figure 1. — Chemical structures of disclosed PROTAC degraders in clinical development. CRBN: cereblon; Ub: ubiquitin; VHL: von Hippel-Lindau