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. 2022 Apr 26;3(2):200–223. doi: 10.37349/etat.2022.00079

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© The Author(s) 2022.

This is an Open Access article licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Figure 2. — Schematic representation of commonly FGFR2 gene fusion in ICC. The most frequent rearrangement partners FGFR2–PPHLN1, FGFR2–AHCYL1, FGFR2–BICC1, and FGFR2–TACC3 are all shown. D: domain; TM: transmembrane region; TK: tyrosine kinase domain; SAM: sterile alpha motif domain