Table 1.

Variables included in the CDM^a conceptual mapping exercise, with counts subsequently reported monthly.

Data item			OMOPb (Y=yes, N=no)		Data source
Demographics
	Gender	Y		Standardized sex (gender) codes are used in OMOP CDM mapping. Date of birth and age concepts also exist.
	Age band	Y		Date of birth and age concepts exist in OMOP.
SESc quintile
	The Index of Multiple Deprivation (IMD, a set of relative measures of deprivation for small areas [lower-layer super-output areas) across England, based on 7 domains of deprivation), in England, the Scottish Index of Multiple Deprivation (SIMD), the Welsh Index of Multiple Deprivation (WIMD), and the Northern Ireland Multiple Deprivation Measure (NIMDM)	N		Does not exist in the OMOP CDM. It can be introduced as a custom mapping in all UK databases within OMOP. It is to be harmonized across the DaC-VaPd data partners (quintile 5 most deprived, quintile 1 least deprived).
Other characteristics
	BMI>30/obesity	Y		Will be found in the measurement table or from a diagnosis of obesity.
	Smoking status	Y		Will be found in the observation table.
Vaccination
	Vaccine type	Y		Will be found in the drug, procedure, and event tables. For England, the source codes are dm+de or SNOMED CTf.
	Vaccine dose	Y		In vaccine administration.
	Vaccination date	Y		Date of event when the event is COVID-19 vaccination.
Exemplar AEIsg
	CVSTh	Y		Will be found in the condition table. It is mapped to SNOMED CT or Read v2. We did not include medications in this feasibility study.
	Anaphylaxis	Y		Will be found in the condition table. It is mapped to SNOMED CT or Read v2. We did not include medications in this feasibility study.

^aCDM: common data model.

^bOMOP: Observational Medical Outcomes Partnership.

^cSES: socioeconomic status.

^dDaC-VaP: Data and Connectivity COVID-19 Vaccines Pharmacovigila.

^edm+d: Dictionary of Medicines and Devices.

^fSNOMED CT: Systematized Nomenclature of Medicine Clinical Trials.

^gAEI: adverse event of interest.

^hCVST: cerebral venous sinus thrombosis.