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. 2022 Aug 24;17(8):e0271926. doi: 10.1371/journal.pone.0271926

Table 4. Circumstances of the experience in the Non-Drug, Psilocybin, LSD, Ayahuasca, and DMT groups1,2.

Non-Drug Psilocybin LSD Ayahuasca DMT
n = 933 n = 766 n = 904 n = 282 n = 307
Duration of Experience (%)
    Five minutes or less 40% 5% a,b 8% a,c 2% b 16% c
    Between 5 minutes and 1 hour 29% 23%a 20%a 21%a 61% b
    1 hour or more 31% 71% a 72% a 77% a 23%b
Medically unconscious at any time during the experience (i.e., completely unresponsive to verbal or physical stimuli) (%) 36% 5% a 9% a 7% a 31%b
Clinically dead (i.e., cessation of breath, heart function) (%) 21% <1% a <1% a <1% a <1% a
Medical professional confirmed to be clinically dead (%) 11% 0% a 0% a 0% a 0% a
Imminent Danger (%)
    Life was in danger and believed it to be at the time 28% 1% a,b 3% a 2% a,b 0% b
    Life was in danger but did not believe it to be at the time 19% 1% a 1% a 0% a 0% a
    Life was not in danger but believed it to be at the time 6% 20%a 21%a 22% a 19%a
    Life was not in danger and did not believe it to be at the time 48% 78% a 75% a 76% a 81% a

1 Comparisons between drug groups were made using general linear model with a logit link and Type III sums of squares including covariates as described in text; pairwise comparisons were adjusted using the Bonferroni method to control for Type I error rate.

2 Bold font = significant difference from the Non-Drug Group (p≤0.001); drug groups not sharing a common letter are significantly different (p≤0.001).