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. 2022 Aug 24;17(8):e0271926. doi: 10.1371/journal.pone.0271926

Table 9. Comparison of experience relative to other lifetime experiences among the Psychedelic Group and the Non-Drug Group.

Non-Drug Psychedelic Regression Analyses1,2
n = 933 n = 2259 β / OR p value
Mean rating relative to other lifetime experiences (range 1–8)3
β
    How personally meaningful was the experience 7.2 (1.1) 6.9 (1.0) -.23 ≤.001
    How spiritually significant was the experience 7.1 (1.4) 6.8 (1.5) -.16 ns
    How personally psychologically insightful was the experience 6.8 (1.8) 6.7 (1.4) -.01 ns
    How psychologically challenging was the experience 5.4 (2.7) 5.5 (2.2) -.10 ns
Percent rating the experience as top 5 most of lifetime
OR
    How personally meaningful was the experience 85% 75% 0.66 ns
    How spiritually significant was the experience 84% 76% 0.65 ≤.001
    How personally psychologically insightful was the experience 78% 72% 0.82 ns
    How psychologically challenging was the experience 54% 47% 0.66 ≤.001
Percent rating the experience as single most of lifetime
OR
    How personally meaningful was the experience 46% 25% 0.42 ≤.001
    How spiritually significant was the experience 50% 38% 0.51 ≤.001
    How personally psychologically insightful was the experience 41% 29% 0.54 ≤.001
    How psychologically challenging was the experience 28% 18% 0.44 ≤.001

1 Each row presents an individual regression analysis for each outcome with group as a factor while controlling for demographic variables as described in text. Coefficients for group are presented as standardized β for linear regressions and odds ratio (OR) for logistic regressions.

2 Bold font = group significant factor in regression analysis at p ≤.001.

3 Rating options ranged from 1 = no more than routine, everyday experience; 5 = similar to experiences that occur on average once every 5 years; 6 = among the 10 most in my life; 7 = among the 5 most of my life; 8 = the single most of my life.