Skip to main content
. 2022 Aug 24;17(8):e0273500. doi: 10.1371/journal.pone.0273500

Fig 1. Serum heme oxygenase (HO)-1 and soluble CD163 (sCD163) with COVID-19.

Fig 1

(A) HO-1 according to disease severity; (B) sCD163 according to disease severity; (C) Comparison of the prediction of severity between HO-1 (red line) and sCD163 (blue line). (A, B) Both serum HO-1 and sCD163 indicated high levels according to the disease severity of COVID-19. The center bold line is the median value; the bottoms and tops of the boxes represent the 25th and 75th percentiles, respectively; and the whiskers are 95% confidence intervals. (C) Comparing the prediction of disease severity between HO-1 and sCD163 (severe vs. moderate and mild), serum HO-1 shows a higher AUC (0.875) than sCD163 (0.733).