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a‐d) Treatment with G9a inhibitors ameliorates motor dysfunction of CL2006 worms. For dose‐response: Values represented are mean ± Standard error of the mean (SEM); n=3 with at least 90–100 worms in each group. Statistical analysis: One‐Way ANOVA, followed by Dunnett post‐hoc analysis. 0 μM Vs. UNC0638 treatment: ***p<0.001; ****p<0.0001. 0 μM Vs. new G9a inhibitor treatment: #p<0.05; ##p<0.01; ###p<0.001; ####p<0.0001.
