Table 3.
Transmission events in participating household contacts in each setting
Household size* | Number of child cases at start of swabbing† | Number of adult cases at start of swabbing | Number of naive contacts |
Number of contacts testing positive |
Naive contact crevicular fluid anti-nucleoprotein total IgG |
|||||
---|---|---|---|---|---|---|---|---|---|---|
Week 1 | Week 2 | Week 3 | Week 4 | Positive on first sample | Positive on last sample | |||||
A | 2 | 1 | 0 | 1 | 0/1 | 0/1 | 0/1 | 0/1 | 0/1 | 0/1 |
B | 3 | 1 | 1 | 1 | 0/1 | 0/1 | 0/1 | 0/1 | 0/1 | 0/1 |
C‡ | 6 | 1 | 0 | 5 | 0/5 | 0/5 | 0/4 | .. | 0/5 | 0/5 |
D§¶ | 4 | 1 | 0 | 3 | 2/3 | 1/3 | 1/3 | 0/3 | 0/3 | 1/3 |
E.1§ | 4 | 1 | 0 | 3 | 0/3 | 0/3 | 0/3 | .. | 0/3 | 0/3 |
E.2‖ | 4 | 1 | 0 | 3 | 1/3 | .. | .. | .. | 0/3 | .. |
E.3§ | 7 | 1 | 0 | 6 | 0/6 | .. | .. | .. | 0/6 | .. |
F | 4 | 2 | 0 | 2 | 1/2 | 2/2 | .. | .. | 0/2 | 0/2 |
G.1§ | 4 | 1 | 0 | 3 | 0/3 | 1/3 | 1/3 | 0/3 | 0/3 | 2/3 |
G.2§ | 3 | 1 | 0 | 2 | 1/2 | 1/2 | 1/1 | 0/1 | 1/2 | 2/2 |
H | 3 | 1 | 2 | 0 | 0/0 | 0/0 | ND | .. | 0/0 | 0/0 |
I | 3 | 1 | 2 | 0 | 0/0 | 0/0 | 0/0 | .. | 0/0 | 0/0 |
J | 4 | 2 | 2 | 0 | 0/0 | 0/0 | 0/0 | .. | 0/0 | 0/0 |
K.1§¶ | 5 | 1 | 0 | 4 | 1/4 | 2/4 | 0/3 | 0/2 | 0/4 | 1/4 |
K.2 | 4 | 2 | 2 | 0 | 0/0 | 0/0 | 0/0 | 0/0 | 0/0 | 0/0 |
M | 3 | 1 | 0 | 2 | 0/2 | 0/2 | 0/2 | .. | 0/2 | 0/2 |
Total | 63 | 19 | 9 | 35 | 6/35 | 7/26 | 3/21 | 0/11 | *1/35 | *6/26 |
Data are n or n/N. A–M and the associated numbers are individual households associated with each educational setting. Where more than one household was associated with a setting, individual households are indicated by an additional number (E.1, E.2, G.1, G.2, K.1, K.2. ..=not done due to intervening holiday or withdrawal from study.
Includes index child case: each household had 100% participation rate at time of consent.
Includes index child case plus any other child already identified as infected.
Naive household contacts include three children.
Naive household contacts include one child.
Household contacts with different genomic sequences to index case are indicated.
Naive household contacts include two children **Proportions are statistically different (p=0·035).)