Table 1.
Characteristics of participants that were studied during the discovery and replication phases
| Discoverya | Replicationb | |||||
|---|---|---|---|---|---|---|
| Male (%) | Female (%) | Total | Male (%) | Female (%) | Total | |
| Controls | 7646 (58.6) | 5411 (41.4) | 13 057 | 5796 (61.0) | 3707 (39.0) | 9503 |
| Cases | 10 172 (60.4) | 6673 (39.6) | 16 845 | 4719 (64.0) | 2659 (36.0) | 7378 |
| Ever smokers | 15 584 (63.9) | 8813 (36.1) | 24 397 | 9230 (67.0) | 4553 (33.0) | 13 783 |
| Never smokers | 2234 (40.6) | 3271 (59.4) | 5505 | 1285 (41.5) | 1813 (58.5) | 3098 |
Samples with European ancestry in INTEGRAL-ILCCO consortium were analyzed in the study. Number of overall lung cancer cases was provided in the table.
aGenotype data from Oncoarray study were used in discovery study.
bGenotype from the other eight studies were used in replication study.