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. 2021 Nov 12;75(1):41–46. doi: 10.1093/cid/ciab895

Table 3.

RV-specific IgA Response to Natural Infection in RV1 Vaccine Failures

RV1 Vaccine Failuresa at Presentation RV1 Vaccine Failures Convalescent Sample
Undetectable RV-specific IgA 29/60 1/60
n, % (95% CI) 48 (36–61) 2 (0.2–11)
RV-specific IgA <20 U/mL 45/60 3/60
n, % (95% CI) 75 (62–85) 5 (2–15)
RV-specific IgA concentrationb Median (IQR,) U/mL 18.8 (6.4–54.7) 433.5 (130.3–896.4)

Abbreviations: IgA, immunoglobulin A; CI, confidence interval; RV, rotavirus; RV1, monovalent oral rotavirus vaccine.

RV gastroenteritis cases with convalescent sample available.

Infants with detectable RV-specific IgA.