Table 3.
Difference of Harrell’s C index between HbA1c variability and FPG variability in predicting HAA/HMA.
| Model 1 | P value | Model 2 | P value | |
|---|---|---|---|---|
| HAA | ||||
| HbA1c variability | 0.6816(0.6606-0.7025) | <0.01* | 0.7078(0.6881-0.7274) | <0.01* |
| FPG variability | 0.6977(0.6773-0.0.7180) | <0.01* | 0.7166(0.6972-0.7360) | <0.01* |
| Difference | 0.0161(0.0085-0.02369) | <0.01* | 0.0882(0.0037-0.01396) | <0.01* |
| HMA | ||||
| HbA1c variability | 0.7102(0.7026-0.7495) | <0.01* | 0.7243(0.7001-0.7574) | <0.01* |
| FPG variability | 0.7271(0.6847-0.7337) | <0.01* | 0.7343(0.7112-0.7575) | <0.01* |
| Difference | 0.0169 | <0.01* | 0.0101 | <0.01* |
*P value<0.05.
Model 1: fasting plasma glucose, HbA1c, age, sex, race plasma glucose control strategy.
Model 2: fasting plasma glucose, plasma glucose control strategy, age, race, female, history of cardiovascular disease, education, depression, cigarette, duration of diabetes, alcohol, body mass index, low-density lipoprotein, high-density lipoprotein, glomerular filtration rate, HbA1c.
HbA1c, glycated hemoglobin A1c; FPG, Fasting plasma glucose; HR, hazard risk; CI, confidence interval; SD, standard deviation; HAA, hypoglycemia requiring any third-party assistance; HMA, hypoglycemia requiring medical assistance.