TABLE 2.
Known and predicted structural features of difficult to express proteins.
| M.bovis | M. tuberculosis | Structure yes (Y), No (N), homology based (H) | Swiss-model | Alphafold Feature | LLPS Probability |
|---|---|---|---|---|---|
| Mb0130 | Rv1003 | H (2–230 of 285) | 3Kwp.1.B | None | 0.19 |
| Mb0854 | Rv0831c | N | Unstructured N-term | 0.2 | |
| Mb1228 | Rv1196 | H (2–175 of 391) | 5xfs.1.B | Unstructured C-term | 0.944 |
| Mb1319 | Rv1288 | H (164–447 of 456) | 6sx4.1.A | Burried N-term | 0.19 |
| Mb1445 | Rv1410c | N | Unstructured C-term | 0.136 | |
| Mb1656 | Rv1630 | Y (283–438 of 481) | 4NNI | Unstructured N-term; highly exteded structure | 0.225 |
| Mb1762 | Rv1733c | N | Unstructured N-term | 0.5 | |
| Mb1916c | Rv1884c | Y (68–153 of 176) | 4OW1 | Unstructured N-term | 0.31 |
| Mb2244 | Rv2220 | Y | 1HTQ | None | 0.19 |
| Mb2410 | Rv2389c | Y (50–127 of 154) | 4ow1.1.A | Unstructured N-term | 0.54 |
| Mb2653 | Rv2620c | N | None | 0.22 | |
| Mb2656 | Rv2623 | Y | 3CIS | None | 0.19 |
| Mb2898 | Rv2873 | Y (58–219 of 220) | 1nyo.1.A | Unstructured N-term | 0.63 |
| Mb2900 | Rv2875 | Y (31–193 of 193) | 1NYO | Unstructured N-term | 0.17 |
| Mb3070 | Rv3044 | H (68–352 of 359) | 3tny.1.A | Unstructured N-term | 0.76 |
| Mb3338 | Rv3310 | H (5–284 of 299) | 1e3c.1.B | Unstructured N-term | 0.2 |
| Mb3644 | Rv3614c | N | Unstructured N-term | 0.46 | |
| Mb3646c | Rv3616c | N | Unstructured C-term | 0.57 | |
| Mb3652 | Rv3628 | Y | 1.WCF | None | 0.18 |
| Mb3871 | Rv3841 | Y | 7O6E | None | 0.13 |