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. 2022 Aug 24;25(8):e25975. doi: 10.1002/jia2.25975

Table 4.

Reasons for PrEP preferences

Characteristic Prefer on‐demand Prefer daily
Easiest PrEP option
Take two pills before sex and one after 314 (41%) 22 (4.2%)
Take two pills after you have sex 97 (13%) 16 (3.1%)
Take two pills before you have sex 339 (44%) 19 (3.6%)
Take a pill every day whether you are having sex or not 16 (2.1%) 464 (89%)
Pay for PrEP if same price as hot meal
No 215 (28%) 164 (32%)
Yes 551 (72%) 357 (69%)
If prefer on‐demand PrEP, why?
I don't like taking tablets everyday
No 175 (23%) 0
Yes 591 (77%) 0
I am not at risk most of the time so would not need PrEP everyday
No 343 (45%) 0
Yes 423 (55%) 0
Less tablets means less chance of getting side effects
No 463 (60%) 0
Yes 303 (40%) 0
Taking PrEP everyday may make people think that I have HIV
No 419 (55%) 0
Yes 347 (45%) 0
There will be less tablets than daily PrEP, so I will be able to store them more
No 518 (68%) 0
Yes 248 (32%) 0
It would be cheaper than taking everyday
No 457 (60%) 0
Yes 309 (40%) 0
Main reason for preferring on‐demand PrEP
I don't like taking tablets everyday 300 (39%) 0
I am not at risk most of the time so would not need PrEP everyday 135 (18%) 0
Less tablets means less chance of getting side effects 77 (10%) 0
Taking PrEP everyday may make people think that I have HIV. On‐demand PrEP is different 117 (15%) 0
There will be less tablets than daily PrEP, so I will be able to store them more easily 30 (3.9%) 0
It would be cheaper than taking everyday 34 (4.4%) 0
Not sure 2 (0.3%) 0
Other 71 (9.3%) 0
If prefer on daily PrEP, why?
I am at risk most of the time so I would need PrEP everyday
No 0 373 (72%)
Yes 0 148 (28%)
Daily PrEP provides protection all the time so I don't need to plan when I have
No 0 124 (24%)
Yes 0 397 (76%)
I think that daily PrEP gives more protection than on‐demand PrEP
No 0 178 (34%)
Yes 0 343 (66%)
I like the routine of daily tablets rather than having to remember PrEP just at
No 0 273 (52%)
Yes 0 248 (48%)
I do not plan sex; therefore, on‐demand PrEP would be difficult to take
No 0 232 (45%)
Yes 0 289 (56%)
To reduce the chance of getting side effects
No 0 414 (80%)
Yes 0 107 (21%)
Main reason for preferring daily PrEP
I am at risk most of the time so I would need PrEP everyday 0 53 (10%)
Daily PrEP provides protection all the time so I don't need to plan when I have sex 0 208 (40%)
I think that daily PrEP gives more protection than on‐demand PrEP 0 115 (22%)
I like the routine of daily tablets rather than having to remember PrEP just at times of sex 0 55 (11%)
I do not plan sex; therefore, on‐demand PrEP would be difficult to take 0 66 (13%)
To reduce the chance of getting side effects 0 18 (3.5%)
Other 0 5 (1.0%)