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. 2022 Aug 11;13:897776. doi: 10.3389/fendo.2022.897776

Figure 2.

Figure 2

Meta-analysis networks for change in HbA1c. Each circle indicates a treatment node. Lines connecting 2 nodes represent direct comparisons between 2 treatments. The size of the nodes is proportional to the number of trials evaluating each treatment. The thickness of the lines is proportional to the number of trials directly comparing the 2 connected treatments. met, metformin; lira_met, liraglutide+metformin; lira, liraglutide; lin5, linagliptin-5 mg; lin1, linagliptin-1 mg; glim, glimepiride; exe1, exenatide-2 mcg; exe2, exenatide-5/10 mcg; dap, dapagliflozin; sita_placebo, sitagliptin+placebo; sita_met, sitagliptin_metformin; sax_met, saxagliptin+metformin.