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. 2022 Aug 11;13:943574. doi: 10.3389/fimmu.2022.943574

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Copyright © 2022 Reitsema, Jiemy, Wekema, Boots, Heeringa, Huitema, Abdulahad, van Sleen, Sandovici, Roozendaal, Diepstra, Kwee, Dasgupta, Brouwer and van der Geest

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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T cells in peripheral blood compartment of patients with PMR. (A) Absolute numbers of CD3⁺ T cells, CD4⁺ T cells, CD8⁺ T cells and (B) CD19⁺ B cells in peripheral blood of 18 patients with PMR and 32 healthy controls (HC). (C) Schematic overview (left panel) of flow cytometric gating for CD45RO^-CCR7⁺ naive (T_Naive), CD45RO⁺CCR7⁺ central memory (T_CM), CD45RO⁺CCR7^- effector memory (T_EM) and CD45RO^-CCR7^- terminally differentiated (T_TD) cells and percentages (right panel) of CD4⁺ and CD8⁺ T_Naive, T_CM, T_EM and T_TD cells in 18 patients with PMR and 32 healthy controls. Statistical significance by Mann-Whitney U test is indicated.