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. 2022 Aug 11;13:937327. doi: 10.3389/fimmu.2022.937327

Table 2.

Recent studies about CAR-T/NK in CSC therapy.

Year Author CSC target Immune cell Tumor References
2015 Zhu et al. CD133 T cell Glioblastoma (57)
2015 Deng et al. EpCAM T cell Prostate cancer (81)
2017 Vita Golubovskaya CD47 T cell Pancreatic cancer (82)
2018 Song et al. CD44/Her-2 T cell Gastric cancer (83)
2018 Wang et al. CLL-1 T cell AML (14)
2018 An et al. CD38 T cell Myeloma (84)
2019 Hu et al. CD133 T cell Glioma (85)
2019 Zhou et al. EpCAM T cell Solid tumor (61)
2019 Zhang et al. EpCAM T cell CRC (62)
2021 Anna Stornaiuolo et al. CD44 T cell Solid tumor (73)
2021 Fu et al. EpCAM T cell Ovarian cancer (60)
2021 Nian et al EpCAM T cell AML (86)
2017 Rüdiger Klapdor et al. CD133 NK92 cell Ovarian cancer (63)
2019 Rüdiger Klapdor et al. CD24 NK92 cell Ovarian cancer (64)
2019 Zhang et al. EpCAM NK92 cell CRC (87)

AML, acute myelocytic leukemia; CRC, colorectal cancer.