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Interactions of kinase inhibitors with CDK2
A. Binding curve of sorafenib with CDK2. B. Binding curve of dasatinib with CDK2. C. Binding curve of imatinib with CDK2. D. Binding curve of pazopanib with CDK2. MST-derived binding curves of NT647-labeled CDK2 to ligands were plotted as a function of ligand concentration. Data are represented as mean ± SD (n = 2). CDK2, cyclin-dependent kinase 2.
