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. 2022 Aug 11;13:974416. doi: 10.3389/fgene.2022.974416

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Copyright © 2022 Niu, Chen, Mi, Mo and Pang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CD8A as a therapeutic biomarker indicating multiple anti-tumor agents’ responsiveness on various cancer cell lines, and cancer cohorts (A) Associations between CD8A expression, and 50% inhibitory concentration (IC₅₀) values of varying antitumor agents or compounds in tumor cell lines based on GDSC and CTRP databases (B) Associations between the expression levels of CD8A, and therapeutic responses to various antitumor drugs in clinical cancer cohorts.