Table 2.

Hazard ratios of heart failure, composite of end points, all-cause mortality, and cause of CV death between patients taking allopurinol and febuxostat.

	Allopurinol		Febuxostat		HR (febuxostat vs. allopurinol)	95 % CI
Variable	No. of event	Incidence (per 1,000 person-year	No. of event	Incidence (per 1,000 person-year		Lower	Upper
Low CV risk group
Primary outcome
Heart failure	541	11.4	947	15.8	1.39	1.25	1.55
Secondary outcome
Composite of end points	1,199	25.2	1,744	29.0	1.15	1.07	1.24
All-cause mortality	656	13.8	869	14.5	1.08	0.97	1.19
Cause of CV death	65.0	1.4	104	1.7	1.35	0.98	1.85
High CV risk group
Primary outcome
Heart failure	523	69.2	840	89.2	1.36	1.22	1.52
Secondary outcome
Composite of end points	886	117.2	1,308	138.9	1.26	1.15	1.37
All-cause mortality	309	40.9	425	45.1	1.11	0.95	1.28
Cause of CV death	56	7.4	83	8.8	1.16	0.83	1.64