Fig. 6.

Examples of follow-up and infection in two patients after vaccination. Time is represented in days with each occurrence (injection of a dose of vaccine or infection) indicated by an arrow. On the left y-axis, plasmas samples were assayed for QuantiFERON SARS-CoV-2 Starter Set® (QFN) Ag1 + 2. Data show the concentration of IFNγ (IU/ml), and are expressed as dot plots, one dot corresponding to one sample with its indicated result, for the same patient. Positive threshold is 0.25 IU/ml (dotted line). On the right x-axis, sera were assayed for S (RBD)-specific IgG. Data show the concentration (BAU/ml) of immunoglobulins, and are expressed as dot plots, one dot corresponding to one sample with its indicated result, for the same patient. Positive threshold is 150 BAU/ml (dotted line). A Results for patient 1, an 87-year-old man who received 3 doses of BNT162b2 given 1 month apart. B Results for patient 2, a 46-year-old woman who had 2 doses of BNT162b2 given 1 month apart