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. 2021 Jun 1;6:135. [Version 1] doi: 10.12688/wellcomeopenres.16789.1

Table 2. Association between antibiotic treatment effectiveness and clinical and bacteriological outcomes.

Characteristic RR (95%CI) p-value aRR (95%CI) p-value
Clinical outcome
Age (years) 0.99 (0.99-1.00) 0.890 0.99 (0.99-1.00) 0.660
Female sex 0.80 (0.68-0.95) 0.012 0.79 (0.64-0.97) 0.023
HIV infected 0.64 (0.48-0.85) 0.002 0.76 (0.59-0.99) 0.048
Duration of symptoms (days) 0.96 0.93-0.98) 0.001 0.97 (0.94-0.99) 0.014
Received effective treatment 1.55 (1.32-1.80) <0.001 1.42 (1.20-1.67) <0.001
Bacteriological outcome
Age (years) 0.99 (0.99-1.01) 0.931 1.00 (0.99-1.01) 0.632
Female sex 0.82 (0.56-1.19) 0.291 0.76 (0.51-1.14) 0.188
HIV infected 0.64 (0.40-1.03) 0.064 0.87 (0.55-1.39) 0.568
Duration of symptoms (days) 0.93 (0.89-0.98) 0.006 0.96 (0.92-1.01) 0.154
Received effective treatment 2.62 (1.89-3.63) <0.001 2.63 (1.77-3.92) <0.001

RR: risk ratio; aRR: adjusted RR; CI: confidence interval; age and duration of symptoms were analysed as continuous variables; duration of symptoms refers to the duration of symptoms prior to the initial clinic presentation (baseline visit).