Table 2.
Clinical characteristics of study patients according to presence of pouch adenomas
|
Characteristic
|
Presence of pouch adenomas (n = 24)
|
Absence of pouch adenomas (n = 71)
|
P
value
|
| Age at time of IPAA [yr, median (IQR)] | 29 (20-40) | 32 (26-41) | 0.10 |
| Sex (male), n (%) | 16 (66.7) | 36 (50.7) | 0.17 |
| No. of colorectal polyps [n, median (IQR)] | 700 (325-1000) | 250 (110-500) | 0.001 |
| Colorectal polyps < 1000, n (%) | 16 (66.7) | 64 (90.1) | 0.006 |
| Colorectal polyps ≥ 1000, n (%) | 8 (33.3) | 7 (9.9) | |
| Time interval after IPAA [mo, median (IQR)] | 142 (106-199) | 116 (91-175) | 0.01 |
| Mucosectomy, n (%) | 19 (79.2) | 53 (74.6) | 0.66 |
| Gastric polyps, n (%) | 19 (79.2) | 51 (71.8) | 0.49 |
| Gastric polyp burden, n (%) | 0.31 | ||
| < 20 | 13 (54.2) | 41 (57.7) | |
| 20-49 | 0 | 11 (15.5) | |
| ≥ 50 | 6 (25.0) | 0 | |
| Duodenal adenomas, n (%) | 16 (66.7) | 30 (42.3) | 0.039 |
| Spigelman stage, n (%) | 0.30 | ||
| I | 6 (37.5) | 18 (60.0) | |
| II | 6 (37.5) | 6 (20) | |
| III | 4 (25.0) | 6 (20) | |
| Desmoid tumor, n (%) | 4 (16.7) | 19 (26.8) | 0.32 |
| NSAIDs use, n (%) | 1 (4.2) | 14 (19.7) | 0.07 |
| Colorectal cancer, n (%) | 9 (37.5) | 34 (47.9) | 0.38 |
IPAA: Ileal pouch anal anastomosis; NSAIDs: Nonsteroidal anti-inflammatory drugs; IQR: Interquartile range.