TABLE 5.

The roles of miR-100-5p in lung disease.

Author	Disease	Target/pathway	Role	Expression	Reference
Wang	Hypoxic pulmonary hypertension	mTOR	Regulate the proliferation of pulmonary artery smooth muscle cells	—	Wang et al. (2015)
Ye	Amyloid ß-induced neuronal pathologies	mTOR pathway	Promote cell apoptosis and affect cell survival	—	Ye et al. (2015)
Frith	—	mTOR pathway	Modulate MSC fate		Frith et al. (2018)
Liu; Peng	PF and liver fibrosis	—	—	↑	Peng et al. (2016); Liu et al. (2018)
Wu	Osteoarthritis	mTOR	Provide a protective effect on articular cartilage and inhibit cell apoptosis	—	Wu et al. (2019)
Dinh	Exosomes from lung spheroid cells	—	—	↑	Dinh et al. (2020)
Wang	MSCs and chronic PM2.5 exposure	—	—	↑	Wang Y. et al. (2021)
Wang	—	—	Inhibit hypoxia-induced proliferation, migration, and phenotype switching of pulmonary artery smooth muscle cells	—	Wang et al. (2020)