Skip to main content
. 2022 Aug 11;13:928933. doi: 10.3389/fphar.2022.928933

TABLE 7.

The roles of miR-29b-3p in lung disease.

Author Disease Target/pathway Role Expression Reference
Deng; He Tissue fibrosis (including heart, liver, lung and kidney) Binding to the 3ʹUTR Inhibit collagen synthesist He et al. (2013); Deng et al. (2017)
Liang; Xue Cardiac fibrosis TGF-β1/SMAD pathway Liang et al. (2019); Xue et al. (2020)
Gong; Tao Liver fibrosis STAT3 Repress collagenous fibrosis Tao et al. (2018); Gong et al. (2020)
Lu Liver fibrosis TGF-β1 Activate COL1A1 expression Lu et al. (2017)
Mullenbrock; Cushing; Pandit PF TGF-β1/SMAD pathway Downregulate miR-29b and promote PF Cushing et al. (2011); Pandit et al. (2011); Cushing et al. (2015); Mullenbrock et al. (2018)
Wan PF Suppress fibroblast proliferation and decrease the level of hydroxyproline Wan et al. (2020)