TABLE 9.
The roles of miR-15a in lung disease.
| Author | Disease | Target/pathway | Role | Expression | Reference |
|---|---|---|---|---|---|
| Tijsen | Cardiac hypertrophy and fibrosis | TGF-β | Exacerbate cardiac hypertrophy and fibrosis | — | Tijsen et al. (2014) |
| Rawal; Jin | Diabetic cardiac fibroblasts | — | Suppress the activation of diabetic cardiac fibroblasts | ↓ | Rawal et al. (2017); Jin (2021) |
| Fu | Hepatic fibrosis | SOX9 | Inhibit LX-2 cell viability and hepatic fibrosis | — | Fu et al. (2022) |
| Chen; Sun | PF | YAP1 | Inhibit the activation of fibroblasts | ↓ | Chen Y. et al. (2019); Sun J. et al. (2019) |
| Kuse | PF | — | — | ↑ | Kuse et al. (2020) |