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editorial
. 2022 Sep;12(9):4346–4360. doi: 10.21037/qims-22-281

Table 5. Cutoff BMD values and T-scores for osteopenia and osteoporosis based on literature data: women’s total hip.

Studies BMDyoung SDyoung Ageold BMDold SDold T-score ≤−1.0 T-score ≤−2.5 Prevalence =29% Prevalence =6.7% §
BMDlow Prevalence (%) BMDos Prevalence (%) BMDlow T-score BMDos T-score
US White [2012] (52)# 0.971 0.114 ≥50 0.830 0.140 0.857 57.55 0.686 15.15
0.971 0.114 ≥60 0.806 0.135 0.857 64.69 0.686 18.74
US Black [2012] (52) 1.036 0.147 ≥50 0.901 0.164 0.889 47.07 0.669 7.86
Canada white [2008] (79) ≥50** 11.3
Argentina [2016] (80) ≥50 6.2
US Amerindian [2016] (81) 50–79 8.4
ML Chinese [2007] (64) 0.956 0.120 50–89 0.851 0.140 0.835 45.55 0.655 8.01 0.774 −1.510 0.641 −2.609
US Chinese [2006] (61) 0.902 0.110 50–89 0.781 0.117 0.792 53.85 0.627 9.42 0.716 −1.689 0.606 −2.695
Hong Kong [2005] (51)^ 0.89 0.11 ≥60 0.751 0.115 0.780 60.00 0.615 11.85 0.699 −1.743 0.599 −2.642
Japan [2001] (63)## 0.886 0.107 50–79 0.748 0.125 0.779 59.87 0.618 14.94 0.679 −1.932 0.561 −3.034
Korea [2014] (66) 0.889 0.102 ≥50 0.765 0.205^^ 0.787 54.20 0.634 26.12 0.652 −2.322 0.458 −4.229

#, cited reference and the year of publication (see reference list). Age in years. BMD unit in g/cm2. **, mean age: 65.0±9.4 (SD) years. , assuming the reference Caucasian have an osteopenia prevalence of 58%, the osteopenia prevalence for Chinese women ≥50 years old is assumed to be 29%. §, based on the US and Canadian Caucasian data and also those of femoral neck results, the osteoporosis prevalence for Chinese women ≥50 years old is assumed to be 6.7%, which could be an aggressive estimation (i.e., the real prevalence could be even lower), as some studies showed hip fragility fracture prevalence of older Chinese women is close to 40% of that of Caucasians (3). Data of Latin American and US Amerindian are listed as reference. Argentina has a high percentage of population with European ancestry. ^, for Hong Kong data, it is assumed that, for subjects ≥60 years, osteopenia prevalence and osteoporosis prevalence is 32.35% and 9.37% respectively. ##, Bow et al. (78) reported that Japanese and Hong Kong Chinese have very similar age-specific hip fragility fracture prevalences. ^^, this SD value is large. BMD, bone mineral density; ML, mainland; BMDyoung, adopted value as the reference BMD; SDyoung, standard deviation of the reference young subject data; BMDold, measured BMD of the subjects ≥50 years old; SDold, standard deviation of the subjects ≥50 years old; BMDlow, the cutpoint to define osteopenia; BMDos, the cutpoint to define osteoporosis.