Table 1. Imaging protocol parameters.
| Parameters | Wfi3d-trig | T1WI | T2WI | DWI | IVIM | APTWI |
|---|---|---|---|---|---|---|
| Sequence | 2D-FSE | 2D-FSE | 2D-FSE | 2D-SS-EPI | 2D-SS-EPI | 2D-FSE |
| Orientation | Axial | Axial | Axial | Axial | Axial | Axial |
| Repetition time/echo time (ms) | 4.92/2.24 | 5.06/2.1 | 3,315/87.8 | 1,620/69.6 | 1,620/69.6 | 4,500/42.56 |
| Field of view (cm2) | 35×50 | 35×50 | 35×50 | 35×50 | 35×50 | 35×50 |
| Matrix | 192×192 | 303×456 | 264×480 | 202×256 | 202×256 | 128×100 |
| Bandwidth (Hz/pixel) | – | 260 | 260 | 2,370 | 2,370 | 500 |
| Slice thickness (mm) | 2 | 5 | 5 | 5 | 5 | 5 |
| Interval (mm) | 0 | 1 | 1 | 1 | 1 | 1 |
| Number of excitations | 2 | 2 | 2 | 1, 8 | 1, 1, 2, 2, 4, 4, 6, 6, 8, 10 | 1 |
| Fat suppression | No | No | Yes | Yes | Yes | No |
| b-values (s/mm2) | – | – | – | 0, 800 | 0, 25, 50, 100, 150, 200, 400, 600, 800, 1,000 | – |
| Respiratory compensation | Yes | Yes | Yes | Yes | Yes | Yes |
| Scan time | 2 min 04 s | 14 s | 2 min 26 s | 2 min 58 s | 3 min 38 s | 3 min 15 s (single slice) |
For APTWI: B1 =1.3 μT and 2.5 μT, ETL =39, Gaussian pulse, 10 repeats, 100 ms duration, plus one S0 with no CEST saturation pulse for normalization, Δ spanned from [−4.5, 4.5] ppm in 31 steps; 11 low power B1 =0.13 μT, Δ spanned from [−1.0, 1.0] ppm images were collected as WASSAR images for B0 map correction. Wfi3d-trig, 3D T1-weighted spoiled gradient-echo sequence with Dixon-based water-fat separation imaging; T1WI, T1-weighted imaging; T2WI, T2-weighted imaging; DWI, diffusion-weighted imaging; IVIM, intravoxel incoherent motion; APTWI, amide proton transfer-weighted imaging; FSE, fast spin echo; SS-EPI, single shot echo planar imaging.